ATXN3 and HDAC6

  • Number of citations of the paper that reports this interaction (PubMedID 24685680)
  • 6

ATXN3

HDAC6

Description ataxin 3 histone deacetylase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 29566793)
  • Coronary artery calcification ( 23870195)
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
  • Height ( 18391950 18391951)
  • Hip circumference adjusted for BMI ( 34021172)
  • LDL cholesterol levels x loop diuretics use interaction ( 31806883)
  • Orofacial clefts ( 22419666)
  • Refractive error ( 32231278)
  • Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes 56 interacting genes: ANXA7 APP ARHGAP19 ARHGDIA ASIC1 CAPN1 CAPN2 CASP1 CDKN1A CHEK1 CSNK2B DNM2 EWSR1 GABARAP GSK3B HDAC6 KAT2B KPNA2 MAP1LC3A MAP1LC3C MAP3K1 MKNK1 NCOR1 NEDD8 PHAF1 PICK1 PJA1 PRKN PSMD7 RAD23A RAD23B RFFL RPS6KA1 SMURF1 SQSTM1 STUB1 SUMO1 TEX11 TK1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TUBA1A TUBB UBB UBC UBE2D3 UBE2L3 UBE2S UBE2W UBE4B UBQLN1 USP21 VCP 86 interacting genes: ADRB2 APOBEC3G ARHGDIA ATF3 ATXN3 AURKA BBS10 BCL3 BCOR BRMS1 CDKN1A CEP70 CSF3 CSNK2A2 CTTN CYLD DYNLL2 EGFR EP300 ERBB2 ERBB3 ERBB4 FBP1 FBXO11 FNTA FNTB GRK2 H3C1 H4-16 HDAC11 HES1 HSP90AA1 HTATIP2 HTATSF1 ISG15 JDP2 KPNA1 LCOR LINC00624 LPXN MAPK1 MAPK3 MAPT MLH1 MSH2 NACAD NASP NR0B2 NR3C1 PLAA POLA2 POLDIP2 POLR1B PPP1CC PRDX4 PRKCZ PRKN PROM1 PTOV1 PXN RELB RNF31 RUNX2 SEPTIN7 SIRT2 SYK TPPP TRIM50 TUBA1A TUBA1B TUBA4A TUBB TUBB2A TUBB2B UBB UBC UBE2D1 UBE2D3 UBE2E1 UBE2H USP10 VCP VKORC1 YWHAZ ZBTB16 ZNF205
Entrez ID 4287 10013
HPRD ID 06131 02228
Ensembl ID ENSG00000066427 ENSG00000094631
Uniprot IDs A0A0A0MS38 C9JQV6 P54252 A0A024QZ26 B4DZH6 Q9BRX7 Q9NSW6 Q9UBN7
PDB IDs 1YZB 2AGA 2DOS 2JRI 2KLZ 4WTH 4YS9 3C5K 3GV4 3PHD 5B8D 5EDU 5KH3 5KH7 5KH9 5WBN 5WPB 6CE6 6CE8 6CEA 6CEC 6CED 6CEE 6CEF
Enriched GO Terms of Interacting Partners?
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