LRRC8E and TRIM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LRRC8E	TRIM3
Description		leucine rich repeat containing 8 VRAC subunit E	tripartite motif containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Ion Channel Complex Integral Component Of Lysosomal Membrane	Cytoplasm Early Endosome Golgi Apparatus Dendrite
	Molecular Function	Volume-sensitive Anion Channel Activity Protein Binding	Protein Binding Protein C-terminus Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Volume Homeostasis Inorganic Anion Transport Aspartate Transmembrane Transport Cellular Response To Osmotic Stress Anion Transmembrane Transport Cyclic-GMP-AMP Transmembrane Import Across Plasma Membrane	Protein Polyubiquitination Nervous System Development Protein Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Miscellaneous transport and binding events	Interferon gamma signaling
Drugs
Diseases
GWAS			Malaria ( 31844061)
Interacting Genes		7 interacting genes: FBXO7 GPSM2 LNX2 NUTM1 SAMD4B TRIM2 TRIM3	34 interacting genes: ACTN4 ASL CDKN1A CEP70 CSNK1D CSNK1E DNMT1 FXR1 FXR2 KCTD7 KIF21B LNX1 LRRC8E MYO5A MYO5B ROPN1 TEAD1 TEAD2 TNFAIP3 TPTEP2-CSNK1E TRIM2 TRIM21 TSC1 UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2G2 UBE2I UBE2K UBE2U UBE2Z USP32
Entrez ID		80131	10612
HPRD ID		08670	05690
Ensembl ID		ENSG00000171017	ENSG00000110171
Uniprot IDs		Q6NSJ5	B7Z5Y8 O75382
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?