SEMA6D and SHF

		SEMA6D	SHF
Description		semaphorin 6D	Src homology 2 domain containing F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Semaphorin Receptor Binding Chemorepellent Activity	Phosphotyrosine Residue Binding
	Biological Process	Neural Crest Cell Migration Axon Guidance Positive Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Smooth Muscle Cell Migration Ventricular System Development Positive Regulation Of Cell Migration Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway	Apoptotic Process
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Antisaccade task score ( 31596458) Attention deficit hyperactivity disorder ( 29325848) Attention deficit hyperactivity disorder or cannabis use ( 30610198) Attention deficit hyperactivity disorder or intracranial volume (pleiotropy) ( 30818988) Attention deficit hyperactivity disorder or putamen volume (pleiotropy) ( 30818988) Body mass index ( 28892062 25673413) Body size at age 10 ( 32376654) Carotid plaque burden (smoking interaction) ( 24954085) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery calcification ( 23870195) Cuneus cortex volume ( 31530798) Diisocyanate-induced asthma ( 25918132) Eating disorders ( 22911880) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Hair greying ( 26926045) Hand grip strength ( 29691431) Heel bone mineral density ( 30598549) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28008999) Lack of perseverance ( 30718321) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung cancer ( 28604730) Lung function (FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Oily fish consumption ( 32066663) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Pericalcarine cortex volume ( 31530798) Phoneme awareness ( 30741946) Pork consumption ( 32066663) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to radiotherapy in cancer (late toxicity) ( 24785509) Restless legs syndrome ( 29029846) Risk-taking tendency (4-domain principal component model) ( 30643258) Rosacea symptom severity ( 29771307) Sleep duration (short sleep) ( 30846698) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (current vs never) ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Ulcerative colitis ( 28008999)	Bisphosphonate-associated atypical femoral fracture ( 31006051) Initial alcohol sensitivity ( 30276832)
Interacting Genes		5 interacting genes: BLOC1S6 C15orf48 PLXNA1 SHF SPATA5L1	3 interacting genes: CHN2 PDGFRA SEMA6D
Entrez ID		80031	90525
HPRD ID		10221	14272
Ensembl ID		ENSG00000137872	ENSG00000138606
Uniprot IDs		A0A185QE25 Q8NFY4	B3KTY1 B4DWP8 B4E1A9 H0YLM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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