SVEP1 and ZFYVE9

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		SVEP1	ZFYVE9
Description		sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	zinc finger FYVE-type containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Membrane	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Calcium Ion Binding	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Lymph Circulation Cell Adhesion Epidermis Development Gene Expression Lymph Vessel Morphogenesis Tie Signaling Pathway Tight Junction Organization	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Blood protein levels ( 30072576 29875488) Coronary artery disease ( 29212778) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Glaucoma (primary open-angle) ( 33627673) Height ( 28552196) Longevity ( 20834067) Mean arterial pressure ( 27618448) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Metamizole-induced agranulocytosis ( 33138277) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Pulse pressure ( 27841878) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Systolic blood pressure ( 27841878 27618448 30578418) Takayasu arteritis ( 33308445) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: ATF7IP FKBP15 MTNR1A SKIL SMAD3 SMAD9 ZFYVE9	40 interacting genes: ANKLE2 ATP6V0B BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NRDC NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		79987	9372
HPRD ID		12942	04782
Ensembl ID		ENSG00000165124	ENSG00000157077
Uniprot IDs		B3KQM1 Q4LDE5 Q5JB40	O95405
PDB IDs			1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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