MCMBP and MCM3

Number of citations of the paper that reports this interaction (PubMedID 17296731)
26

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology)

		MCMBP	MCM3
Description		minichromosome maintenance complex binding protein	minichromosome maintenance complex component 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cell Junction	Chromosome, Telomeric Region Nucleus Nucleoplasm Alpha DNA Polymerase:primase Complex Nucleolus Centrosome Membrane MCM Complex Perinuclear Region Of Cytoplasm CMG Complex
	Molecular Function	Chromatin Binding Protein Binding	DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Single-stranded DNA Helicase Activity
	Biological Process	DNA-dependent DNA Replication Sister Chromatid Cohesion Cell Division	Double-strand Break Repair Via Break-induced Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication DNA Duplex Unwinding Mitotic DNA Replication Initiation
Pathways			Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Height ( 28552196)	Cryptococcosis in HIV infection ( 33269293)
Interacting Genes		15 interacting genes: ASL DBF4 DDIT3 FKBP5 KEAP1 MCM3 MCM4 MCM5 MCM6 MCM7 PRTFDC1 RWDD2A SNW1 USP7 ZNF474	37 interacting genes: CCNE1 CDC45 CDC5L CDC6 CDC7 CDK2 CSNK2A1 DBF4 EP300 HAUS1 KEAP1 LZTR1 MAPK6 MCM10 MCM2 MCM3AP MCM4 MCM5 MCM6 MCM7 MCMBP ORC2 ORC4 ORC5 PLK1 POLR2A PPP2R1A PPP2R1B PTEN RAD52 STAT1 SUMO2 SUPT16H SYF2 TFAP2B TRIM28 YWHAQ
Entrez ID		79892	4172
HPRD ID		07624	04072
Ensembl ID		ENSG00000197771	ENSG00000112118
Uniprot IDs		A0A0S2Z5P5 Q9BTE3	A0A0S2Z4T1 A0A499FHX9 B4DUQ9 P25205
PDB IDs		4KG9	6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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