EPM2A and HMGXB4

Number of citations of the paper that reports this interaction (PubMedID 26493215)
7

Data Source:
BioGRID (two hybrid)

		EPM2A	HMGXB4
Description		EPM2A glucan phosphatase, laforin	HMG-box containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	NURF Complex
	Molecular Function	Protein Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases
GWAS		Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)	Hip circumference adjusted for BMI ( 34021172 25673412) Hip index ( 34021172) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		15 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS	27 interacting genes: AKAP17A CACNA1I CREBBP DNAL4 EPM2A H3-4 HABP4 INO80B JMJD6 LENG8 MX1 NKAPD1 NR1H2 PIAS2 SRPK2 STAC3 STRBP SUMO2 TAB1 TENT5B TNNT1 TSC22D1 TSPYL2 UBE2I UBL5 UROD ZCCHC10
Entrez ID		7957	10042
HPRD ID		06345	05267
Ensembl ID		ENSG00000112425	ENSG00000100281
Uniprot IDs		H0UI04 O95278	Q7Z641 Q9UGU5
PDB IDs		4R30 4RKK
Enriched GO Terms of Interacting Partners?
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