HMGXB4 and STRBP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HMGXB4	STRBP
Description		HMG-box containing 4	spermatid perinuclear RNA binding protein
Image		No pdb structure
GO Annotations	Cellular Component	NURF Complex	Manchette Nucleus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding Microtubule Binding
	Biological Process	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway	Spermatid Development Mechanosensory Behavior
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172 25673412) Hip index ( 34021172) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Birth weight ( 27680694) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 31562340 31217584) Lymphocyte counts ( 32888494)
Interacting Genes		27 interacting genes: AKAP17A CACNA1I CREBBP DNAL4 EPM2A H3-4 HABP4 INO80B JMJD6 LENG8 MX1 NKAPD1 NR1H2 PIAS2 SRPK2 STAC3 STRBP SUMO2 TAB1 TENT5B TNNT1 TSC22D1 TSPYL2 UBE2I UBL5 UROD ZCCHC10	59 interacting genes: ADARB1 ARNT CAMK2G DAB1 EIF2AK2 HMGXB4 LRRK2 MAP4 MIR1-1 MIR1-2 MIR106A MIR122 MIR128-2 MIR138-1 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR199A1 MIR199A2 MIR19A MIR200A MIR200B MIR200C MIR214 MIR221 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR429 MIR7-1 MIR7-3 MIR9-1 MIR9-3 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G PRKRA RBFOX1 RBPMS RBPMS2 STAU1 THAP1 ZMAT4 ZNF346
Entrez ID		10042	55342
HPRD ID		05267	10257
Ensembl ID		ENSG00000100281	ENSG00000165209
Uniprot IDs		Q7Z641 Q9UGU5	A0A0S2Z5K8 Q96SI9 V9HWK4
PDB IDs			2DMY
Enriched GO Terms of Interacting Partners?
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