MALL and ELOVL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MALL	ELOVL2
Description		mal, T cell differentiation protein like	ELOVL fatty acid elongase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Raft	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Myelination Cholesterol Homeostasis	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Alpha-linolenic Acid Metabolic Process Very Long-chain Fatty Acid Biosynthetic Process Linoleic Acid Metabolic Process
Pathways			Linoleic acid (LA) metabolism alpha-linolenic acid (ALA) metabolism Synthesis of very long-chain fatty acyl-CoAs
Drugs			alpha-Linolenic acid
Diseases
GWAS			Adverse response to drug ( 30420678) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Glycerophospholipid levels ( 26068415) Metabolic traits ( 21886157) Metabolite levels ( 22916037) Phospholipid levels (plasma) ( 22359512) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		70 interacting genes: AMIGO1 AQP6 ARL13B ATP5PF BEST2 BNIP3 BNIP3L BRI3 BSCL2 CAV1 CAV2 CD79A CLDN7 CLDN9 CLEC10A CLEC12B CLEC14A CPLX4 CREB3 CREB3L1 CRHR2 CTLA4 DAGLA DCBLD2 ELOVL2 ELOVL4 EMP1 EVI2A FCGR1A FFAR2 FNDC9 GGT7 GJA8 GPA33 IL7R KASH5 KLRC1 LDLRAD1 LEPROTL1 LMNA MANBAL MCEMP1 MS4A12 MSR1 MUC1 NEK9 OPRM1 PGRMC2 PLA2G2E RETREG3 RNF185 SIGLEC6 SIT1 SLC10A1 SLC10A6 SLC18A1 SLC35C2 STMN4 STX1A SYNE4 SYT2 TMEM139 TMEM182 TMEM248 TMEM31 TMEM80 TMX2 UBE2I VPS11 ZP3	4 interacting genes: FXYD6 IFITM3 MALL TMEM218
Entrez ID		7851	54898
HPRD ID		15997	16857
Ensembl ID		ENSG00000144063	ENSG00000197977
Uniprot IDs		Q13021	A0A024QZV3 Q9NXB9
PDB IDs
Enriched GO Terms of Interacting Partners?
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