CACNB2 and PRMT5

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

CACNB2

PRMT5

Description calcium voltage-gated channel auxiliary subunit beta 2 protein arginine methyltransferase 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Antisaccade task score ( 31596458)
  • Apolipoprotein B levels ( 32203549)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood pressure ( 21909110)
  • Body mass index ( 28892062)
  • Brain volume in infants (grey matter) ( 28763065)
  • Cadmium levels ( 26025379)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diastolic blood pressure ( 19430479 27841878 21909115 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diverticular disease ( 30177863)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Hypertension ( 31879980 19430479 21909115)
  • LDL cholesterol levels ( 32203549)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328)
  • Primary tooth development (time to first tooth eruption) ( 23704328)
  • Protein quantitative trait loci ( 18464913)
  • Pulse pressure ( 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Quantitative traits ( 19197348)
  • Response to antiepileptic drugs in genetic generalized epilepsy ( 32308125)
  • Schizophrenia ( 28991256 25056061 29483656 30285260 23974872)
  • Small vessel stroke ( 26732560)
  • Systolic blood pressure ( 28135244 19430479 27841878 21909115 28739976 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • White matter hyperintensity volume ( 33293549)
  • Cortical amyloid beta load ( 29860282)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes 13 interacting genes: C10orf67 CTBP2 GPR85 HEXIM2 MSRB2 NEBL NRP1 PDIA3 PRKACA PRMT5 PTER REM1 TMEM174 93 interacting genes: ARGLU1 C1orf109 CACNB2 CALU CAPN1 CDC37 CDK19 CDK8 CDYL2 CLK1 CLK3 CLNS1A CTDP1 DIO3 DNMT3A DUSP14 EIF4A1 EIF4A3 ELOA EPHB6 EZH2 FAM76B GAS8 GLI1 GRHL3 GTPBP2 H2AC20 H2AC4 H3-4 H3-5 H3C1 H4-16 H4C1 HOXC4 ILF3 ING5 JAK1 JAK2 JAK3 KANK2 LDHAL6B LENG8 LNX1 LUC7L MAGEB2 MBP MCRS1 MEF2D MYOD1 MYOG NCL NELFCD NTAQ1 NUDCD2 OLA1 PDCD4 PDGFRA PHYHIP POLR2A PRPF38A RBM23 RSRP1 SF3A3 SIN3A SLU7 SMARCA2 SMARCB1 SMARCC1 SMARCE1 SNRNP70 SNRPB SNRPD1 SNRPD3 SPAG8 SREBF1 SSTR1 STUB1 SUPT5H TRIB3 TRIM54 TYK2 UBE3A WDR5 WDR77 YWHAG YWHAQ YWHAZ ZDHHC17 ZMYND19 ZNF2 ZNF224 ZNF436 ZUP1
Entrez ID 783 10419
HPRD ID 02473 04955
Ensembl ID ENSG00000165995 ENSG00000100462
Uniprot IDs A0A494C0B2 A0A494C184 Q08289 Q59H42 Q5VVH1 B4DV00 O14744
PDB IDs 4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S 6RLL 6RLQ 6UGH 6UXX 6UXY 6V0N 6V0O 6V0P
Enriched GO Terms of Interacting Partners?
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