CACNA1A and KALRN

  • Number of citations of the paper that reports this interaction (PubMedID 21078624)
  • 26
  • Data Source:
  • BioGRID (two hybrid)

CACNA1A

KALRN

Description calcium voltage-gated channel subunit alpha1 A kalirin RhoGEF kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Exfoliation syndrome ( 25706626)
  • Proteinuria and chronic kidney disease ( 26420894)
  • Acute graft versus host disease in bone marrow transplantation (donor effect) ( 27595289)
  • Amyotrophic lateral sclerosis ( 26580837)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Diffuse large B-cell lymphoma or systemic lupus erythematosus ( 31407831)
  • General cognitive ability ( 29844566)
  • Hematocrit ( 32888494)
  • Heschl's gyrus morphology ( 25130324)
  • Intraocular pressure ( 29617998 29785010 31959993)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Longevity (age >99th survival percentile) ( 31413261)
  • Low urine pH ( 30476138)
  • Lymphocyte counts ( 32888494)
  • Marginal zone lymphoma or systemic lupus erythematosus ( 31407831)
  • Mean platelet volume ( 22139419 32888494 27863252)
  • Metabolite levels ( 23823483)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Monocyte count ( 32888494)
  • Myocardial infarction ( 33532862)
  • Neutrophil percentage of white cells ( 32888494)
  • Platelet count ( 32888494 27863252)
  • Platelet distribution width ( 32888494 27863252)
  • Plateletcrit ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Red cell distribution width ( 32888494)
  • Schizophrenia ( 30285260)
  • Stroke ( 32693751)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (1df test) ( 32227373)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373)
  • Thyroid peroxidase antibody levels ( 24586183)
  • Urine pH measurement ( 30476138)
Interacting Genes 92 interacting genes: ABCA2 ABI1 ACTN1 ADGRL1 AGRN ALDOA AMIGO2 AP2M1 ARHGAP22 BTG3 C1QTNF1 CABP1 CACNB1 CACNB4 CALM2 CALM3 CKAP5 CRIM1 CRMP1 CSNK2B CYSRT1 DNAJB5 EFEMP1 EFEMP2 EHMT2 EIF3A FBLN1 GET3 GNB1 GOLGA6L5P GRN HECW1 HHATL HIVEP1 HSPG2 IP6K1 JAG2 KALRN KHDRBS3 KIAA1191 LAMB1 LLGL1 LRP1 LTBP1 LTBP3 LTBP4 MANBAL MATK MATN2 MEGF6 MEGF8 MIA3 MOAP1 NDUFB8 NELFCD NELL1 NELL2 NOTCH1 NOXA1 OLIG1 PCSK5 PCSK6 PMM1 PPIG PPM1A PPP1R12C PTGDS PUF60 RBM12B RIMBP2 RPL31 RPS17 SCP2 SPRY1 SRRM4 SRSF1 SUMF2 SYT1 TAF15 TELO2 TSC22D1 TSPAN7 TSPOAP1 TUBB2B UQCRC2 VARS1 VPS52 VWF WBP1 YLPM1 ZCCHC17 ZNF233 16 interacting genes: ATXN7 CACNA1A CDC5L COIL DISC1 DTNBP1 ENO3 EPHB2 FASLG GFI1B LNX1 NDEL1 PAM SPTAN1 SUMO2 SUMO3
Entrez ID 773 8997
HPRD ID 03004 06859
Ensembl ID ENSG00000141837 ENSG00000160145
Uniprot IDs A0A087WW63 B5TYJ1 O00555 Q9NS89 C9IZQ6 O60229
PDB IDs 3BXK 5QQD 5QQE 5QQF 5QQG 5QQH 5QQI 5QQJ 5QQK 5QQL 5QQM 5QQN 5QU9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?