PCGF2 and CBX6

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		PCGF2	CBX6
Description		polycomb group ring finger 2	chromobox 6
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex	Nucleus Nucleoplasm Chromosome PcG Protein Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding Promoter-specific Chromatin Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Anterior/posterior Pattern Specification Histone Acetylation Histone H2A-K119 Monoubiquitination Embryonic Skeletal System Morphogenesis Cellular Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways		SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6	Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS			Bladder cancer ( 24163127 20972438) Plateletcrit ( 32888494)
Interacting Genes		24 interacting genes: ABHD6 CBX6 CCND2 CD247 CTNNAL1 GJB5 HOXC9 HSF2 LMNA OGT PELI2 RBCK1 RING1 RNF2 SPDEF STX2 TRAF2 UBE2D3 UBE2E2 UBE2Q2 UBE2T UBE2U USP11 USP7	3 interacting genes: HOXC9 PCGF2 PCGF6
Entrez ID		7703	23466
HPRD ID		10621	13005
Ensembl ID		ENSG00000277258	ENSG00000183741
Uniprot IDs		A0A024R1V6 P35227	B0QXZ6 O95503
PDB IDs			3GV6 3I90
Enriched GO Terms of Interacting Partners?
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