XRCC1 and CHD1L

Number of citations of the paper that reports this interaction (PubMedID 33053171)
0

Data Source:
BioGRID (fluorescent resonance energy transfer, fluorescent resonance energy transfer)

		XRCC1	CHD1L
Description		X-ray repair cross complementing 1	chromodomain helicase DNA binding protein 1 like
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Nucleolus ERCC4-ERCC1 Complex	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Enzyme Binding Oxidized DNA Binding 3' Overhang Single-stranded DNA Endodeoxyribonuclease Activity	Nucleotide Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Single Strand Break Repair Response To Hypoxia Base-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Xenobiotic Stimulus Response To Organic Substance Negative Regulation Of Protein ADP-ribosylation Cerebellum Morphogenesis Hippocampus Development Response To Hydroperoxide Voluntary Musculoskeletal Movement Telomeric DNA-containing Double Minutes Formation Positive Regulation Of Single Strand Break Repair Positive Regulation Of DNA Ligase Activity Negative Regulation Of Protection From Non-homologous End Joining At Telomere Replication-born Double-strand Break Repair Via Sister Chromatid Exchange	DNA Repair Chromatin Remodeling Cellular Response To DNA Damage Stimulus DNA Duplex Unwinding
Pathways		Resolution of AP sites via the single-nucleotide replacement pathway APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway HDR through MMEJ (alt-NHEJ) Gap-filling DNA repair synthesis and ligation in GG-NER Gap-filling DNA repair synthesis and ligation in TC-NER	Formation of Incision Complex in GG-NER Dual Incision in GG-NER
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Height ( 31562340) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)	Height ( 31562340) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25760438)
Interacting Genes		20 interacting genes: APEX1 APLF APTX BRCA1 BTRC CHD1L CSNK2A1 CSNK2A2 LIG3 NEIL1 OGG1 PARP1 PARP2 PCNA PNKP POLB PSMD8 RNF146 TOPORS UBE2I	9 interacting genes: BAALC CTCF NR4A1 PARP1 PDE4DIP SCYL1 SRPK2 TRIM33 XRCC1
Entrez ID		7515	9557
HPRD ID		01909	09880
Ensembl ID		ENSG00000073050	ENSG00000131778
Uniprot IDs		B2RCY5 P18887 Q59HH7	A0A0A0MRH8 A0A0A0MSH9 Q86WJ1
PDB IDs		1CDZ 1XNA 1XNT 2D8M 2W3O 3K75 3K77 3LQC 5E6Q 5W7X 5W7Y 6WH1 6WH2	6ZHX 6ZHY
Enriched GO Terms of Interacting Partners?
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