TUBG1 and RPGR

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
HPRD (in vivo)

		TUBG1	RPGR
Description		tubulin gamma 1	retinitis pigmentosa GTPase regulator
Image
GO Annotations	Cellular Component	Pericentriolar Material Condensed Nuclear Chromosome Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Microtubule Cytoplasmic Microtubule Cell Leading Edge Ciliary Basal Body Apical Part Of Cell Recycling Endosome Non-motile Cilium Mitotic Spindle Microtubule	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Identical Protein Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Cytoplasmic Microtubule Organization	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs		Vinblastine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		35 interacting genes: APP BRCA1 CENPJ CNTN2 CTRL CUL4A DDX41 IKBKG KIF14 KRT18 KRT19 MARK4 NAPG NDE1 OGT PCNT PHB PIK3R1 PLK1 PXN RACGAP1 RACK1 RARA RASSF1 RND2 RNF19A RPGR SGCA SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4 WNT3	19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE
Entrez ID		7283	6103
HPRD ID		01853	02425
Ensembl ID		ENSG00000131462	ENSG00000156313
Uniprot IDs		P23258	Q92834
PDB IDs		1Z5V 1Z5W 3CB2 6V5V 6V6S 7AS4	4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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