RPGR and IFT88

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
HPRD (in vivo)

		RPGR	IFT88
Description		retinitis pigmentosa GTPase regulator	intraflagellar transport 88
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Centrosome Centriole Cytosol Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Sperm Flagellum Ciliary Tip Ciliary Base Non-motile Cilium
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Kinesin Binding
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly	Kidney Development Intraciliary Transport Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Cilium Assembly Non-motile Cilium Assembly Regulation Of Autophagosome Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases
GWAS			Coronary artery calcification ( 23870195) Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE	17 interacting genes: ALDH8A1 CACNA1C CAPN7 CCDC120 EEF2KMT EML2 FBXO7 ITPKB MAP4K5 MSRB1 PCOTH PDX1 PRRC2A RPGR SAP18 SMARCE1 TRIM24
Entrez ID		6103	8100
HPRD ID		02425	09000
Ensembl ID		ENSG00000156313	ENSG00000032742
Uniprot IDs		Q92834	A0A140VJL7 B3KX42 Q13099
PDB IDs		4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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