TSC1 and TANK

  • Number of citations of the paper that reports this interaction (PubMedID 21653829)
  • 98
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

TSC1

TANK

Description TSC complex subunit 1 TRAF family member associated NFKB activator
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol consumption ( 27911795)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronotype ( 30696823)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Dietary macronutrient intake ( 23372041)
  • Educational attainment ( 25201988)
  • Educational attainment (years of education) ( 23722424)
  • Extremely high intelligence ( 29520040)
  • General cognitive ability ( 29844566)
  • Household income (MTAG) ( 31844048)
  • Obesity-related traits ( 23251661)
  • Presence of antiphospholipid antibodies ( 23509613)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Subcutaneous adipose tissue ( 22589738)
  • Tourette syndrome ( 30818990)
  • Treatment response for severe sepsis ( 22310353)
  • Weight ( 31647587)
Interacting Genes 179 interacting genes: ABI1 ACTN1 ACTN2 AKT1 ANKIB1 ANKRD24 ANKRD35 APPL2 AQP1 ARAF ARID5A ATN1 ATXN1 AURKA AXIN1 BAG3 BCL11A BECN1 BEND5 BRD3 C1orf94 CALCOCO2 CAPZA2 CASC3 CCDC120 CCDC88B CCL28 CCNB1 CCND2 CCNE1 CDK1 CDK4 CDK6 CDKN2A CDKN2B CDR2 CHCHD2 CNIH1 CNTRL CNTROB COG6 CSTF2 CTNNB1 DACH2 DCTN2 DMRT3 DOK5 EIF3A ENKD1 EZR FAM110A FAM222B FBF1 FCN1 FGFR4 FOLR2 FOXH1 FRS3 GCC1 GEMIN8 GFAP GLIS2 GOLGA2 GPANK1 GPATCH1 HECW1 HGS HNRNPM HOMER3 HOOK2 HOXC8 HR HSH2D ICA1 IGFN1 IKBKB KANSL2 KAT2A KAZN KDM1A KIF1C KIF5A KLC1 KLC4 LATS2 LENG1 LMO2 LRSAM1 LUC7L LZTS2 MAP2K5 MAPK14 MBIP MBP MSANTD3 MSN MT-ND1 MYC MYLIP MYOZ3 NDUFA9 NECAB2 NEFL NF2 NINL NKD2 NRBF2 PAEP PATL1 PATZ1 PHLDB1 PICK1 PITX1 PLK1 PLK2 POGZ POU6F2 PPFIA2 PPP1R18 PPP1R32 PRMT6 PTPA RALYL RASSF1 RBPMS RDX RHEB RIN1 RIN3 RUNDC3A SAMD11 SAMD7 SCMH1 SEC31A SELENOW SERTAD1 SH2D2A SHANK1 SHC3 SLC16A6 SMG9 SORBS3 SOX4 SPAG5 SPAG8 SUOX TANK TBC1D7 TBX6 TCF7L2 TFAP2D TFIP11 TLE5 TNS2 TRAF2 TRIM3 TRIOBP TSC2 TSGA10IP TSHZ3 TUBB4B VENTX VEZF1 VGLL3 VIM VPS37C YPEL3 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZIC1 ZNF417 ZNF423 ZNF587 ZNF765 ZNF79 33 interacting genes: AIMP2 APBA3 APP ATP6V1H BIK CD40 CHUK COPB1 FBLN1 HLA-C IKBKB IKBKE IKBKG INPP5K KPNA2 LAMC1 LRP2 MAP4K5 MARCHF5 PLK1 RACGAP1 SDC4 SMAD3 SRSF11 TBK1 TP53BP2 TRAF1 TRAF2 TRAF3 TRAF6 TSC1 USP7 ZC3H12A
Entrez ID 7248 10010
HPRD ID 05594 04870
Ensembl ID ENSG00000165699 ENSG00000136560
Uniprot IDs A0A2R8Y5S3 Q32NF0 Q86WV8 Q92574 X5D9D2 B2R7S3 Q6NW12 Q92844
PDB IDs 4Z6Y 5EJC 7DL2 1KZZ 1L0A 5H10
Enriched GO Terms of Interacting Partners?
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