INS-IGF2 and CLN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		INS-IGF2	CLN5
Description		INS-IGF2 readthrough	CLN5 intracellular trafficking protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Lysosome Lysosomal Membrane Endoplasmic Reticulum Golgi Apparatus Cytosol Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Hormone Activity	Protein Binding Mannose Binding Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process	Signal Transduction	Signal Peptide Processing Lysosome Organization Lysosomal Lumen Acidification Brain Development Neurogenesis Protein Catabolic Process Retrograde Transport, Endosome To Golgi Neuron Maturation Glycosylation Positive Regulation Of GTP Binding
Pathways
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth weight ( 31043758) Cervical cancer ( 31488892) Cervical cancer (MTAG) ( 31488892) Estimated glomerular filtration rate ( 31152163) Fasting glucose ( 34059833) Glycated hemoglobin levels ( 34059833) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Length of menstrual cycle ( 30202859) Red blood cell count ( 32888494) Type 1 diabetes ( 30572963) Type 2 diabetes ( 28838971 25102180 30718926)	Blood protein levels ( 30072576) Major depressive disorder ( 34099189) Morning vs. evening chronotype ( 26835600) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		2 interacting genes: CLN5 GPR152	9 interacting genes: FDFT1 GPR152 IGF2 INS-IGF2 OGT PLPP6 SLC41A1 SLC41A2 TMEM31
Entrez ID		723961	1203
HPRD ID		18989	07619
Ensembl ID		ENSG00000129965	ENSG00000102805
Uniprot IDs		F8WCM5	A0A024R644 O75503
PDB IDs			6R99
Enriched GO Terms of Interacting Partners?
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