CLN5 and SLC41A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLN5	SLC41A2
Description		CLN5 intracellular trafficking protein	solute carrier family 41 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Golgi Apparatus Cytosol Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Mannose Binding Hydrolase Activity, Acting On Glycosyl Bonds	Protein Binding Magnesium Ion Transmembrane Transporter Activity
	Biological Process	Signal Peptide Processing Lysosome Organization Lysosomal Lumen Acidification Brain Development Neurogenesis Protein Catabolic Process Retrograde Transport, Endosome To Golgi Neuron Maturation Glycosylation Positive Regulation Of GTP Binding	Magnesium Ion Transmembrane Transport
Pathways			Metal ion SLC transporters
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Major depressive disorder ( 34099189) Morning vs. evening chronotype ( 26835600) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
Interacting Genes		9 interacting genes: FDFT1 GPR152 IGF2 INS-IGF2 OGT PLPP6 SLC41A1 SLC41A2 TMEM31	32 interacting genes: AQP6 CD79A CKAP4 CLN5 CREB3 EBP ERGIC3 ERVFRD-1 FATE1 FNDC9 FUT3 GJA5 GJB5 GPR151 GPR42 GPX8 IGFBP5 IL27RA KASH5 KIR3DL3 LDLRAD1 LEUTX LIME1 LMNA LY6G6C LYVE1 MFF PDCD1LG2 PVR SHISAL1 SSMEM1 TMEM237
Entrez ID		1203	84102
HPRD ID		07619	15389
Ensembl ID		ENSG00000102805	ENSG00000136052
Uniprot IDs		A0A024R644 O75503	Q96JW4
PDB IDs		6R99
Enriched GO Terms of Interacting Partners?
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