TRPC1 and HOMER3

Number of citations of the paper that reports this interaction (PubMedID 14505576)
150

Data Source:
BioGRID (pull down)

		TRPC1	HOMER3
Description		transient receptor potential cation channel subfamily C member 1	homer scaffold protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex Receptor Complex	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite
	Molecular Function	Signaling Receptor Binding Cation Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity ATPase Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding
	Biological Process	Calcium Ion Transport Manganese Ion Transport Melanin Biosynthetic Process Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cytosolic Calcium Ion Concentration Response To Calcium Ion Calcium Ion Transmembrane Transport Regulation Of Cardiac Conduction	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways		TRP channels Role of second messengers in netrin-1 signaling Ion homeostasis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: BMPR2 CAV1 GRIA1 HOMER1 HOMER3 ITPR2 ITPR3 MDFI MX1 PKD2 RHOA TRPC3 TRPC4 TRPC5	92 interacting genes: ABI1 ABI2 ABI3 APP ARL13B C1orf116 C4orf17 CCDC120 CCDC141 CCDC187 CDC37 CDK18 CEBPB CWF19L2 DVL3 DYNLL1 DYNLL2 EAF1 EFHC1 EIF3D FAM161B FAM90A1 FAT1 FBXO28 FMR1 FRYL FXR1 FXR2 GAS8 GDF15 GGN GRM5 HOMER1 HOXB5 INCA1 ITPR1 KANK2 KANK4 KDM1A KRTAP19-7 LHX2 LNX1 LRRC7 LSM14B MDM1 MEOX1 MFAP1 MIA3 MOS MSS51 NEBL NTAQ1 OTX2 PALLD PAX6 PAX7 PKN1 PLAAT5 POLI POM121 PPP1R18 PPP1R32 PRCC PRR35 PSMA1 PSMA2 PSMC5 PSORS1C2 RBM14 RBM22 RUNX1T1 RYR1 SAXO1 SCNM1 SDCBP SHANK3 SLAIN1 SMR3B SNRPF SRPK2 TBC1D22B TOX2 TRPC1 TSC1 USP2 WBP2 WIPF1 ZBTB4 ZNF19 ZNF35 ZNF414 ZNF655
Entrez ID		7220	9454
HPRD ID		11894	07270
Ensembl ID		ENSG00000144935	ENSG00000051128
Uniprot IDs		P48995	Q9NSC5
PDB IDs			2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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