TPM2 and MAST2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		TPM2	MAST2
Description		tropomyosin 2	microtubule associated serine/threonine kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton	Cytoplasm Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Actin Binding Structural Constituent Of Muscle Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding Protein Serine Kinase Activity
	Biological Process	Muscle Contraction Actin Filament Organization Regulation Of ATPase Activity	Protein Phosphorylation Cytoskeleton Organization Peptidyl-serine Phosphorylation Regulation Of Interleukin-12 Production Intracellular Signal Transduction Spermatid Differentiation
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Platelet count ( 32888494) White blood cell count ( 32888494)	Blood protein levels ( 28240269) Body mass index ( 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Granulocyte count ( 27863252) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Red blood cell count ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Serum metabolite levels ( 33031748) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Sum basophil neutrophil counts ( 27863252) Type 2 diabetes ( 32499647)
Interacting Genes		22 interacting genes: ABI2 ACTA1 ACTB FARS2 GRK2 JUN MAST2 MESD MRFAP1 NEB PDLIM7 PIK3CG RRAD S100A2 S100A4 SKIL SNAPIN TFPT TPM1 ZNF229 ZNF620 ZNF785	29 interacting genes: ACE2 ACTN2 APP CD200 CD48 CDHR2 DYNLL1 IPO13 KDM4A MXRA7 PTEN RPS27A RPS6KA1 SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 SRPK2 STK36 SUMO2 TK1 TPM1 TPM2 TPM3 TRAF2 TRAF6 TTN ZNF417
Entrez ID		7169	23139
HPRD ID		11768	11294
Ensembl ID		ENSG00000198467	ENSG00000086015
Uniprot IDs		A7XZE4 P07951 Q5TCU3 V9HW25	A0A669KBJ4 Q6P0Q8
PDB IDs			2KQF 2KYL
Enriched GO Terms of Interacting Partners?
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