TNNI1 and PKD2L1

Number of citations of the paper that reports this interaction (PubMedID 12809519)
5

Data Source:
BioGRID (pull down)

		TNNI1	PKD2L1
Description		troponin I1, slow skeletal type	polycystin 2 like 1, transient receptor potential cation channel
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Cytoplasmic Vesicle Calcium Channel Complex Intracellular Membrane-bounded Organelle Receptor Complex Ciliary Membrane Non-motile Cilium
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding	Calcium Activated Cation Channel Activity Cation Channel Activity Calcium Channel Activity Sodium Channel Activity Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cation Transmembrane Transporter Activity Calcium-activated Potassium Channel Activity Sour Taste Receptor Activity Identical Protein Binding Muscle Alpha-actinin Binding Alpha-actinin Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste Cation Transport Smoothened Signaling Pathway Response To Water Sodium Ion Transmembrane Transport Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Sensory Perception Of Sour Taste Detection Of Mechanical Stimulus Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS			Body shape index ( 34021172) Coronary artery disease ( 29212778 33020668) Diastolic blood pressure ( 30224653) Fatty acid desaturase activity (adipose tissue) ( 30453627) Glycerophospholipid levels ( 26068415) Heel bone mineral density ( 30598549 28869591) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 32888494) Macular thickness ( 30535121) Mean platelet volume ( 32888494 27863252) Obesity-related traits ( 23251661) Palmitic acid (16:0) levels ( 23362303) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303) Phospholipid levels (plasma) ( 22359512) Red cell distribution width ( 32888494) Refractive error ( 32231278) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748 24625756) Serum metabolite levels (CMS) ( 31636271) Serum metabolite ratios in chronic kidney disease ( 29545352) Squamous cell lung carcinoma ( 28604730) Vaccenic acid (18:1n-7) levels ( 28298293)
Interacting Genes		48 interacting genes: ACTA1 ANKRD11 ARMC7 C2orf68 CABP2 CABP5 CCDC102B CCDC57 CCDC85B CDCA7L CEP19 CETN3 CTNNA3 DCAF11 DCC EAF1 EFCAB2 EIF1AD EIF3B ENKD1 ESRRG KIFC3 L3MBTL2 MBD3 MCRS1 MDFI MNS1 MTUS2 NEK7 PIH1D2 PIK3R3 PKD2L1 PNMA1 POLR1C PRKAB2 SAT1 SCNM1 SPANXN2 SYCE1L TNNC1 TNNT1 TNNT2 TPM3 TRIM41 TRIM55 TRIM63 USP20 ZNF76	4 interacting genes: CLDN19 TNNI1 TNNI2 TNNI3
Entrez ID		7135	9033
HPRD ID		01842	16063
Ensembl ID		ENSG00000159173	ENSG00000107593
Uniprot IDs		P19237	Q1L4F0 Q9P0L9
PDB IDs			3TE3 4GIF 6DU8
Enriched GO Terms of Interacting Partners?
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