TGFB2 and TGFBR2

  • Number of citations of the paper that reports this interaction (PubMedID 8106553)
  • 81
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

TGFB2

TGFBR2

Description transforming growth factor beta 2 transforming growth factor beta receptor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181 30542056)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Bone mineral density (hip) ( 30172743)
  • Central corneal thickness ( 32528159 29760442)
  • Chronic obstructive pulmonary disease ( 28166215 30804561)
  • Chronic obstructive pulmonary disease (severe) ( 24621683)
  • Diastolic blood pressure ( 30224653)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Emphysema imaging phenotypes ( 26030696)
  • FEV1 ( 30804560)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Heel bone mineral density ( 30598549)
  • Height ( 20881960 25282103 25429064 31562340)
  • Hip circumference adjusted for BMI ( 34021172 25673412)
  • Hip minimal joint space width ( 27701424)
  • Intraocular pressure ( 29617998)
  • Local histogram emphysema pattern ( 25006744)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Peak expiratory flow ( 30804560)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Refractive error ( 32231278)
  • Rosacea symptom severity ( 29771307)
  • Systolic blood pressure ( 30578418)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
  • Breast cancer ( 29059683 23535729)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Metabolite levels ( 23823483)
  • Migraine ( 22683712 27322543)
  • Migraine - clinic-based ( 23793025)
  • Night sleep phenotypes ( 27126917)
  • Postprandial triglyceride response ( 32603185)
  • Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
  • Systolic blood pressure ( 30224653)
  • Tonometry ( 17903302)
Interacting Genes 17 interacting genes: APP BMP2 CCN2 DCN ENG FMOD KMT2A LTBP3 MARK1 PZP TGFB1 TGFB3 TGFBR1 TGFBR2 TGFBR3 VASN VTN 50 interacting genes: ACVR1 ACVRL1 AP2B1 APP ARHGEF6 ARHGEF7 CCNB1 CCNB2 CD44 CDK1 CLU CTNNB1 DAB2 DAXX DYNLT4 EIF3I ENG FANCC GOPC KCNK18 MAP2K1 NRP1 OSR1 PAK1 PDGFRA PIK3R1 PIK3R2 PML PPP2CB PSMD14 RCVRN SMAD3 SMAD4 SMAD7 SNX6 STRAP TDGF1 TERT TGFB1 TGFB1I1 TGFB2 TGFB3 TGFBR1 TGFBR3 TGFBRAP1 TRAP1 TRMO TSSK1B ZFYVE9 ZNF510
Entrez ID 7042 7048
HPRD ID 01828 01823
Ensembl ID ENSG00000092969 ENSG00000163513
Uniprot IDs P61812 Q59EG9 A3QNQ0 D2JYI1 P37173
PDB IDs 1TFG 2TGI 4KXZ 5TX4 5TY4 6I9J 1KTZ 1M9Z 1PLO 2PJY 3KFD 4P7U 4XJJ 5E8V 5E8Y 5E91 5E92 5QIN 5TX4 5TY4
Enriched GO Terms of Interacting Partners?
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