TAFAZZIN and RPL10

		TAFAZZIN	RPL10
Description		tafazzin, phospholipid-lysophospholipid transacylase	ribosomal protein L10
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Membrane	Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Protein-containing Complex
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Translation Regulator Activity
	Biological Process	Mitophagy Heart Morphogenesis Muscle Contraction Mitochondrion Organization Inner Mitochondrial Membrane Organization Heart Development Skeletal Muscle Tissue Development Hemopoiesis Cardiolipin Metabolic Process Cardiolipin Biosynthetic Process Mitochondrial Respiratory Chain Complex I Assembly Cardiolipin Acyl-chain Remodeling Cristae Formation Mitochondrial ATP Synthesis Coupled Electron Transport Spermatocyte Division Cardiac Muscle Tissue Development Cardiac Muscle Contraction Positive Regulation Of Cardiolipin Metabolic Process Positive Regulation Of ATP Biosynthetic Process	Ribosomal Large Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Cytoplasmic Translation Translation Regulation Of Translation Negative Regulation Of Apoptotic Process Embryonic Brain Development
Pathways		Mitochondrial protein import Mitochondrial protein import Acyl chain remodeling of CL	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS
Interacting Genes		16 interacting genes: BTRC CCDC88C CHGB CSNK1E GSK3B LATS1 LATS2 OPN1LW RPL10 RUNX1 SLC6A8 SLC9A3R2 SSR4 TRAK2 VBP1 YWHAE	16 interacting genes: DUX4 ERCC6 FYN HCK LYN MAPK6 OGT PRKCA PTEN RAD21 SRC SUMO2 TAB1 TAFAZZIN TBPL1 YES1
Entrez ID		6901	6134
HPRD ID		02316	02421
Ensembl ID		ENSG00000102125	ENSG00000147403
Uniprot IDs		A0A0S2Z4E6 A0A0S2Z4F4 A0A0S2Z4K0 A0A0S2Z4K9 A0A494C0C5 A0A499FJ53 A6XNE1 Q16635	P27635 X5D2T3
PDB IDs			2PA2 5AJ0 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6W6L
Enriched GO Terms of Interacting Partners?
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