TAFAZZIN and LATS2

Number of citations of the paper that reports this interaction (PubMedID 20858893)
212

Data Source:
BioGRID (enzymatic study)

		TAFAZZIN	LATS2
Description		tafazzin, phospholipid-lysophospholipid transacylase	large tumor suppressor kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Membrane	Spindle Pole Nucleus Cytosol Centriolar Satellite
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Mitophagy Heart Morphogenesis Muscle Contraction Mitochondrion Organization Inner Mitochondrial Membrane Organization Heart Development Skeletal Muscle Tissue Development Hemopoiesis Cardiolipin Metabolic Process Cardiolipin Biosynthetic Process Mitochondrial Respiratory Chain Complex I Assembly Cardiolipin Acyl-chain Remodeling Cristae Formation Mitochondrial ATP Synthesis Coupled Electron Transport Spermatocyte Division Cardiac Muscle Tissue Development Cardiac Muscle Contraction Positive Regulation Of Cardiolipin Metabolic Process Positive Regulation Of ATP Biosynthetic Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Hormone-mediated Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-serine Phosphorylation Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Localization To Nucleus
Pathways		Mitochondrial protein import Mitochondrial protein import Acyl chain remodeling of CL	Signaling by Hippo
Drugs
Diseases
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: BTRC CCDC88C CHGB CSNK1E GSK3B LATS1 LATS2 OPN1LW RPL10 RUNX1 SLC6A8 SLC9A3R2 SSR4 TRAK2 VBP1 YWHAE	68 interacting genes: ABL1 AJUBA AKT1 ARAF ARNT AURKA AURKB BECN1 BRAF CBLC CCND2 CCNE1 CD44 CDK2 CDK4 CDK6 CDKN1A CDKN2A CDKN2B CDKN2C CHEK1 CHEK2 CTNNB1 DYRK1A EPHA2 ERBB2 EZH2 FGFR4 FHL3 FLT1 FZR1 GLIS1 GLIS2 GRAP2 GRM1 HGF HIF1A KAT2A KDELR2 KIF23 MAP2K3 MAP2K5 MAPK14 MDM4 MET MOB3A MOB3B MOB3C MOB4 MYC NF2 NFIC PDGFRA RAF1 RASSF1 RELA SMAD2 SNAI1 STK11 STK3 SUZ12 TAFAZZIN TEAD2 TP53 TSC1 WWTR1 YWHAG YWHAZ
Entrez ID		6901	26524
HPRD ID		02316	07277
Ensembl ID		ENSG00000102125	ENSG00000150457
Uniprot IDs		A0A0S2Z4E6 A0A0S2Z4F4 A0A0S2Z4K0 A0A0S2Z4K9 A0A494C0C5 A0A499FJ53 A6XNE1 Q16635	A0A024RDM3 Q9NRM7
PDB IDs			4ZRI
Enriched GO Terms of Interacting Partners?
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