MAP3K7 and PPP5C

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

MAP3K7

PPP5C

Description mitogen-activated protein kinase kinase kinase 7 protein phosphatase 5 catalytic subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil percentage of white cells ( 27863252)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Hemoglobin ( 32888494)
  • Lymphocyte counts ( 32888494)
  • Neuroticism ( 29255261)
  • Response to antidepressants in depression ( 29998114)
  • Triglyceride levels ( 32203549)
Interacting Genes 71 interacting genes: AKTIP ATIC BBS10 BCL10 CALML6 CARD11 CHUK COPS5 CYLD EIF2AK2 ELP1 EZH2 FBXL4 FOS GPR25 HGS HIPK2 IKBKB IL17RD IRAK1 MAILR MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS MUL1 NAIP NDUFS6 NFKBIA NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB SUPT20H TAB1 TAB2 TGFBR1 TNFRSF11A TRAF3 TRAF3IP2 TRAF6 UBASH3A UBC USP4 VRK2 XIAP ZNF593 ZNF746 27 interacting genes: APP CDC16 CDC27 CDC37 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L CSNK1D DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A HUWE1 MAP3K5 MAP3K7 MAPT OGT PPP2R1A PPP2R3A VHL
Entrez ID 6885 5536
HPRD ID 04011 02805
Ensembl ID ENSG00000135341 ENSG00000011485
Uniprot IDs O43318 A0A024R0Q7 P53041
PDB IDs 2EVA 2YIY 4GS6 4L3P 4L52 4L53 4O91 5E7R 5GJD 5GJF 5GJG 5J7S 5J8I 5J9L 5JGA 5JGB 5JGD 5JH6 5JK3 5V5N 1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 4ZVZ 4ZX2 5HPE 5UI1 5WG8
Enriched GO Terms of Interacting Partners?
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