PPP5C and GNA12

  • Number of citations of the paper that reports this interaction (PubMedID 12176367)
  • 44
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)
  • HPRD (in vivo, two hybrid, in vitro)

PPP5C

GNA12

Description protein phosphatase 5 catalytic subunit G protein subunit alpha 12
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil percentage of white cells ( 27863252)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Hemoglobin ( 32888494)
  • Lymphocyte counts ( 32888494)
  • Neuroticism ( 29255261)
  • Response to antidepressants in depression ( 29998114)
  • Triglyceride levels ( 32203549)
Interacting Genes 27 interacting genes: APP CDC16 CDC27 CDC37 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L CSNK1D DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A HUWE1 MAP3K5 MAP3K7 MAPT OGT PPP2R1A PPP2R3A VHL 30 interacting genes: ACTB AGTR1 AKAP13 APP ARAF ARHGEF11 ARHGEF12 BTK CDH1 CDH15 CDH2 DRD5 F2R GNA13 GNB1 HSP90AA1 IL3RA NAPA PPP2R1A PPP5C PRKCA PRKCB PRKCD PRKCE RASA2 S1PR4 S1PR5 TBXA2R TEC TSHR
Entrez ID 5536 2768
HPRD ID 02805 05093
Ensembl ID ENSG00000011485 ENSG00000146535
Uniprot IDs A0A024R0Q7 P53041 E9PC54 Q03113 Q6ZQV4
PDB IDs 1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 4ZVZ 4ZX2 5HPE 5UI1 5WG8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?