AURKA and CDH13

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

AURKA

CDH13

Description aurora kinase A cadherin 13
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adiponectin levels ( 20876611 22479202 22065538 31178129 20887962 21771975 24105470)
  • Adolescent idiopathic scoliosis ( 31417091 30395268)
  • Adult body size ( 32376654)
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145)
  • Alcohol consumption (heavy vs. light/non-drinkers) ( 27911795)
  • Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780)
  • Attention deficit hyperactivity disorder ( 18839057)
  • Bipolar disorder ( 31043756)
  • Blood pressure ( 17903302)
  • Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778 30104761 28714974 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Crohn's disease ( 28067908)
  • D-dimer levels ( 21502573)
  • Daytime sleep phenotypes ( 27126917)
  • Declining hemoglobin trajectory in blood donors ( 33491795)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Depression (quantitative trait) ( 20800221)
  • Diastolic blood pressure ( 27841878 31170924 30578418)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Erectile dysfunction ( 30583798)
  • Feeling hurt ( 29500382)
  • Feeling tense ( 29500382)
  • Fish- and plant-related diet ( 32066663)
  • Gait speed in old age ( 28077804)
  • General risk tolerance (MTAG) ( 30643258)
  • Glucose homeostasis traits ( 25524916)
  • Gut microbiota relative abundance (Blautia) ( 33208821)
  • Gut microbiota relative abundance (Prevotella) ( 33208821)
  • Height ( 20189936)
  • Hippocampal volume ( 31530798)
  • Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828)
  • Hypertension ( 19304780)
  • Hypothyroidism ( 27182965)
  • IgE levels in asthmatics (D.f. specific) ( 23967269)
  • Leukoderma in response to rhododendrol ( 32558222)
  • Maximal oxygen uptake response ( 25729143)
  • Myocardial infarction ( 33532862)
  • Night sleep phenotypes ( 27126917)
  • Oily fish consumption ( 32066663)
  • Periodontitis (Mean PAL) ( 24024966)
  • Pork consumption ( 32066663)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • PR interval ( 32439900)
  • Precuneus cortex volume ( 31530798)
  • Pulse pressure ( 28135244 27841878 28739976 30578418)
  • Rapid automised naming of digits ( 30741946)
  • Refractive astigmatism ( 30306274)
  • Response to amphetamines ( 22952603)
  • Response to antipsychotic treatment ( 20195266)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Response to fenofibrate (adiponectin levels) ( 23149075)
  • Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
  • Schizophrenia ( 23358160)
  • Seasonality and depression ( 30217971)
  • Short-term memory (digit-span task) ( 30741946)
Interacting Genes 170 interacting genes: AATF AKT1 ANGPTL4 ANP32B APP ARPC1B ARPC2 ATRX AUNIP AURKAIP1 BAAT BCL2L1 BEX2 BIRC5 BLID BORA BRAF BRCA1 BTK CBX3 CCND2 CCNE1 CDC20 CDC25B CDH13 CDK8 CHFR CKAP5 CORO2A CSN2 CTCFL CYLC2 DACH1 DKK3 EHMT2 EPHA2 EPSTI1 ERBB2 ERRFI1 FANCA FBP2 FOXF1 FOXP1 FZR1 GADD45A GMNN GSK3B GTF3C4 H3-4 H3C1 HDAC2 HDAC6 HEMGN HIF1A HNRNPF HNRNPK IFI16 IGFBP3 IKBKB INCENP KIF11 KIF2C KLHL18 KLK5 LATS2 LEF1 LYPD3 MAP2K1 MAP2K3 MAP3K5 MAPK3 MAPRE2 MAPRE3 MBD3 MBP MDM2 MED26 MTA3 MYC MYT1 MYT1L NANS NAT2 NDC80 NEDD9 NF2 NFKBIA NFXL1 NIN NKX1-1 NME1 NSD2 NUF2 OTUB1 OTUD7B PARP10 PAX4 PAX8 PDGFRA PDLIM2 PLK3 PML POU4F3 PPP1CA PPP1CB PPP1CC PPP2CB PPP3R2 PRKACA PSEN2 PSMC3IP PTPRD PTTG1 PUM2 RASA1 RASSF1 RELA REST S100A14 SCGB3A1 SEC61B SFRP4 SIN3B SOX18 SOX3 SOX30 SOX4 SREBF2 SRPK1 SRPK2 SSRP1 STAT2 STK11 STX17 SUPT20H SWT1 TACC1 TACC3 TBC1D2 TBX10 TCEAL2 TCERG1 TCF3 TEAD2 TFAP2B TGFB1 THRSP TLK1 TLK2 TP53 TP73 TPX2 TRMO TRRAP TSC1 TSTD2 UBE2C UBE2I UBE2N UBTF USP2 USP21 VHL WIF1 XPA YY1 ZFHX3 ZKSCAN2 ZNF189 ZNF510 10 interacting genes: ADIPOQ AURKA CASP8 CCND1 CHEK2 HMMR MAPK6 MTNR1B PTPN1 RAD51
Entrez ID 6790 1012
HPRD ID 04066 03219
Ensembl ID ENSG00000087586 ENSG00000140945
Uniprot IDs O14965 B7Z3H7 B7Z9B1 P55290
PDB IDs 1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2DWB 2J4Z 2J50 2NP8 2W1C 2W1D 2W1E 2W1F 2W1G 2WQE 2WTV 2WTW 2X6D 2X6E 2X81 2XNE 2XNG 2XRU 3COH 3E5A 3EFW 3FDN 3H0Y 3H0Z 3H10 3HA6 3K5U 3LAU 3M11 3MYG 3NRM 3O50 3O51 3P9J 3QBN 3R21 3R22 3UNZ 3UO4 3UO5 3UO6 3UOD 3UOH 3UOJ 3UOK 3UOL 3UP2 3UP7 3VAP 3W10 3W16 3W18 3W2C 4B0G 4BN1 4BYI 4BYJ 4C3P 4C3R 4CEG 4DEA 4DEB 4DED 4DEE 4DHF 4J8M 4J8N 4JAI 4JAJ 4JBO 4JBP 4JBQ 4O0S 4O0U 4O0W 4PRJ 4UYN 4UZD 4UZH 4ZS0 4ZTQ 4ZTR 4ZTS 5AAD 5AAE 5AAF 5AAG 5DN3 5DNR 5DOS 5DPV 5DR2 5DR6 5DR9 5DRD 5DT0 5DT3 5DT4 5EW9 5G15 5G1X 5L8J 5L8K 5L8L 5LXM 5OBJ 5OBR 5ODT 5ONE 5ORL 5ORN 5ORO 5ORP 5ORR 5ORS 5ORT 5ORV 5ORW 5ORX 5ORY 5ORZ 5OS0 5OS1 5OS2 5OS3 5OS4 5OS5 5OS6 5OSD 5OSE 5OSF 5ZAN 6C2R 6C2T 6C83 6CPE 6CPF 6CPG 6GRA 6HJJ 6HJK 6I2U 6R49 6R4A 6R4B 6R4C 6R4D 6VPG 6VPH 6VPI 6VPJ 6VPL 6VPM 6XKA 6Z4Y 7AYH 7AYI 2V37
Enriched GO Terms of Interacting Partners?
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