TRIM21 and TRIM8

  • Number of citations of the paper that reports this interaction (PubMedID 22493164)
  • 7
  • Data Source:
  • BioGRID (two hybrid)

TRIM21

TRIM8

Description tripartite motif containing 21 tripartite motif containing 8
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Brain morphology (MOSTest) ( 32665545)
  • Feeling nervous ( 29500382)
  • Hip circumference adjusted for BMI ( 34021172)
  • Prostate cancer ( 23535732)
  • Pulse pressure ( 30578418)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 30285260)
  • Serum alkaline phosphatase levels ( 33547301)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Ulcerative colitis ( 26192919)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 70 interacting genes: ALOX15B APC CALR CASP8AP2 CBX4 CDC34 CUL1 CWC25 DAXX DCP2 DMAP1 DZIP3 EHHADH ELAVL1 EXOC8 FADD FBXW11 FHOD1 GABARAP GABARAPL1 GABARAPL2 GMCL1 GRAP HLA-DRB1 IGFN1 IGHG1 IGHV4-31 IKBKB IRF5 IRF8 LNX1 MAP1LC3A MAP1LC3B MAP1LC3C MNAT1 NIF3L1 PFKP RBCK1 RNF111 RO60 SAMHD1 SETD7 SKP2 SQSTM1 TBK1 TCP11L1 TH TNS4 TRIM27 TRIM3 TRIM39 TRIM5 TRIM8 TXN2 UBC UBE2C UBE2D1 UBE2D2 UBE2E1 UBE2H UBE2I UBE2L3 USP15 USP2 USP4 VPS9D1 XAF1 YJU2 YWHAZ ZBTB16 64 interacting genes: ADD3 BRAP CATSPER1 CBL CCNH DCUN1D1 ESR1 FAM124B HOXA1 ITSN1 LNX1 LONRF1 MAGEC2 MKRN3 MSL2 MTURN NUDT10 OTUB2 PCGF5 RAD18 RAD23A RC3H2 RCHY1 RNF111 RNF113A RNF138 RNF141 RNF168 RNF181 RNF41 RNF7 SIAH1 SOCS1 TICAM1 TNFAIP3 TNPO2 TNS2 TRAF5 TRIM15 TRIM2 TRIM21 TRIM24 TRIM25 TRIM39 TRIM43 TRIM47 TRIM9 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L6 UBE2V1 UBE2W UBXN7 UHRF2 USP2 USP21 USP39 USP5 USP7 XIAP YOD1
Entrez ID 6737 81603
HPRD ID 00170 06934
Ensembl ID ENSG00000132109 ENSG00000171206
Uniprot IDs P19474 Q9BZR9
PDB IDs 2IWG 5JPX 5OLM 6FGA 6S53 7BBD
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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