TRIM8 and ADD3

TRIM8

ADD3

Description tripartite motif containing 8 adducin 3
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Brain morphology (MOSTest) ( 32665545)
  • Feeling nervous ( 29500382)
  • Hip circumference adjusted for BMI ( 34021172)
  • Prostate cancer ( 23535732)
  • Pulse pressure ( 30578418)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 30285260)
  • Serum alkaline phosphatase levels ( 33547301)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Ulcerative colitis ( 26192919)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 64 interacting genes: ADD3 BRAP CATSPER1 CBL CCNH DCUN1D1 ESR1 FAM124B HOXA1 ITSN1 LNX1 LONRF1 MAGEC2 MKRN3 MSL2 MTURN NUDT10 OTUB2 PCGF5 RAD18 RAD23A RC3H2 RCHY1 RNF111 RNF113A RNF138 RNF141 RNF168 RNF181 RNF41 RNF7 SIAH1 SOCS1 TICAM1 TNFAIP3 TNPO2 TNS2 TRAF5 TRIM15 TRIM2 TRIM21 TRIM24 TRIM25 TRIM39 TRIM43 TRIM47 TRIM9 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2L6 UBE2V1 UBE2W UBXN7 UHRF2 USP2 USP21 USP39 USP5 USP7 XIAP YOD1 13 interacting genes: AGTR1 ATXN1 CWF19L1 GNG13 HSPB1 OPRM1 PENK PRKCA RPL4 TRIM8 TUBGCP4 UBE2I ZNF76
Entrez ID 81603 120
HPRD ID 06934 03339
Ensembl ID ENSG00000171206 ENSG00000148700
Uniprot IDs Q9BZR9 Q53FL4 Q59EK1 Q5VU08 Q9UEY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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