DDRGK1 and FASTKD5

		DDRGK1	FASTKD5
Description		DDRGK domain containing 1	FAST kinase domains 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule Mitochondrial Nucleoid
	Molecular Function	Protein Binding Ubiquitin-like Protein Ligase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Binding Protein Binding RRNA Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Cartilage Development Reticulophagy Protein Localization To Endoplasmic Reticulum Protein Ufmylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of I-kappaB Phosphorylation Negative Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Metallopeptidase Activity Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Protein K69-linked Ufmylation	Mitochondrial RNA Processing MRNA Processing Regulation Of Mitochondrial MRNA Stability
Pathways		RHOA GTPase cycle
Drugs
Diseases
GWAS		HDL cholesterol levels x loop diuretics use interaction ( 31806883) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Night sleep phenotypes ( 27126917) Parkinson's disease ( 25064009 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Response to hepatitis C treatment ( 21659334) Ribavirin-induced anemia ( 20637204)	Household income ( 31844048) Household income (MTAG) ( 31844048) Night sleep phenotypes ( 27126917)
Interacting Genes		5 interacting genes: APP FASTKD5 FBXO7 HTR6 TP53	15 interacting genes: CCDC85B DDRGK1 EBF4 KCNH1 MAVS MID2 MRPS26 MTUS2 NRSN2 NSFL1C PCED1A SIRPG SLC24A3 TRIM27 ZNF343
Entrez ID		65992	60493
HPRD ID		12741	07813
Ensembl ID		ENSG00000198171	ENSG00000215251
Uniprot IDs		Q96HY6	Q7L8L6
PDB IDs
Enriched GO Terms of Interacting Partners?
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