RSRC2 and UPF2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		RSRC2	UPF2
Description		arginine and serine rich coiled-coil 2	UPF2 regulator of nonsense mediated mRNA decay
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cytosol Polysome Exon-exon Junction Complex Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Telomeric DNA Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Animal Organ Regeneration
Pathways			Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Diverticular disease ( 30177863)
Interacting Genes		21 interacting genes: AKAP9 APP CMTM5 CTAG1A CTAG1B GOLGA2 KASH5 NAV1 OGT PFDN5 PNMA1 RINT1 SAMD4B SRPK1 SRPK2 TRIM23 TRIM54 UBQLN1 UBQLN2 UBQLN4 UPF2	78 interacting genes: ABCF2 AGPAT1 AKTIP ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GATA3 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MTREX MYB NDUFA7 NOB1 NOMO1 NOP53 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SMG1 SSBP2 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44
Entrez ID		65117	26019
HPRD ID		13342	10405
Ensembl ID		ENSG00000111011	ENSG00000151461
Uniprot IDs		B3KMH4 Q7L4I2	Q9HAU5
PDB IDs			1UW4 2WJV 4CEK 4CEM
Enriched GO Terms of Interacting Partners?
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