SKIL and ZMYM2

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		SKIL	ZMYM2
Description		SKI like proto-oncogene	zinc finger MYM-type containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Nucleoplasm Transcription Regulator Complex Protein-containing Complex	Cytosol PML Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding SMAD Binding	Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Lymphocyte Homeostasis Transforming Growth Factor Beta Receptor Signaling Pathway Spermatogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Response To Cytokine Negative Regulation Of Cell Differentiation Positive Regulation Of Axonogenesis Regulation Of Cell Cycle Lens Fiber Cell Differentiation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Biological_process
Pathways		Downregulation of SMAD2/3:SMAD4 transcriptional activity Downregulation of SMAD2/3:SMAD4 transcriptional activity	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Estimated glomerular filtration rate ( 31152163) Glomerular filtration rate (creatinine) ( 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Prostate cancer ( 21743467)	Adult body size ( 32376654) Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)
Interacting Genes		96 interacting genes: ASCC3 CAMSAP1 CBX4 CDC16 CDC27 CHD3 CHPF COL4A2 CPNE1 CPNE2 CPNE4 CXXC5 DEUP1 DHX30 DRG1 EEF1G EIF4G2 ESR1 FAF1 FBLN1 FN1 FZR1 GAS8 GLUL GOLGB1 HEY1 HEYL HIPK1 HIPK3 HNRNPLL IL36RN KRT81 LRP1 MACF1 MORC4 MVP MYG1 NCOR1 NCOR2 NEFL NID1 NID2 NXF3 OIP5 PAPPA PIAS1 PIAS3 PIAS4 PLCD3 PPL PSG3 PSMC2 PTPRF PYCR2 RNF4 RPS27 SASH1 SETDB1 SKI SMAD1 SMAD2 SMAD3 SMAD4 SMUG1 SMURF2 SNRNP70 SNX17 SPARCL1 SRP72 STK16 SVEP1 TDG TDP2 TFPI2 THAP5 THSD7A TLE5 TPM2 TRAK1 TRIM62 TRIM69 TSKU TTF2 UBE2I UIMC1 USP25 VPS28 XPA XRCC6 ZBTB3 ZBTB6 ZMYM2 ZMYM5 ZNF106 ZNF200 ZZEF1	26 interacting genes: CEBPE CREB1 CREBBP FBXL17 FUS GMCL1 HNRNPA2B1 HNRNPH3 IKZF3 PAICS PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B
Entrez ID		6498	7750
HPRD ID		01319	03745
Ensembl ID		ENSG00000136603	ENSG00000121741
Uniprot IDs		P12757	A0A024RDS3 A8K126 Q9UBW7
PDB IDs		3EQ5 5C4V
Enriched GO Terms of Interacting Partners?
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