RMND5A and MAEA

Number of citations of the paper that reports this interaction (PubMedID 29911972)
27

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		RMND5A	MAEA
Description		required for meiotic nuclear division 5 homolog A	macrophage erythroblast attacher, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm GID Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Actin Binding Ubiquitin-protein Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Cytoskeleton Organization Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Enucleate Erythrocyte Development Cell Division
Pathways
Drugs			Tetrachlorodecaoxide
Diseases
GWAS		High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Fasting glucose ( 34059833) Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 32499647 22158537 30718926 28869590)
Interacting Genes		6 interacting genes: APP GID8 MAEA MEOX2 SMAD9 VKORC1	11 interacting genes: ARMC8 GID4 GID8 GSK3A MKLN1 MYOC RANBP10 RMND5A UBE2D3 UBE2H UBE2R2
Entrez ID		64795	10296
HPRD ID		07841	08427
Ensembl ID		ENSG00000153561	ENSG00000090316
Uniprot IDs		Q9H871	B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9
PDB IDs
Enriched GO Terms of Interacting Partners?
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