IFT22 and KMT2E

		IFT22	KMT2E
Description		intraflagellar transport 22	lysine methyltransferase 2E (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Endomembrane System Intraciliary Transport Particle B Ciliary Tip	Chromatin Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Plasma Membrane Nuclear Body Nuclear Speck Protein-containing Complex Transcriptionally Active Chromatin
	Molecular Function	GTPase Activity GTP Binding	Protein Binding Histone-lysine N-methyltransferase Activity Enzyme Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport	Neutrophil Mediated Immunity DNA Methylation Chromatin Organization Cell Cycle Erythrocyte Differentiation Neutrophil Activation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Histone H3-K4 Trimethylation
Pathways		Intraflagellar transport Intraflagellar transport	PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Autism spectrum disorder ( 30804558) Autism spectrum disorder or schizophrenia ( 28540026) General risk tolerance (MTAG) ( 30643258) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil count ( 32888494) Schizophrenia ( 29483656)
Interacting Genes		1 interacting genes: KMT2E	12 interacting genes: ALKBH4 ASH2L ATP13A1 CDK1 CYP2C18 FIS1 IFT22 LAMTOR5 MAPRE2 NFE4 TRAPPC14 ZCWPW1
Entrez ID		64792	55904
HPRD ID		15204	10528
Ensembl ID		ENSG00000128581	ENSG00000005483
Uniprot IDs		A0A024QYT8 A0A024QYV3 Q9H7X7	Q8IZD2
PDB IDs			2LV9 4L58 5HT6
Enriched GO Terms of Interacting Partners?
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