SH3BP2 and VAV3

  • Number of citations of the paper that reports this interaction (PubMedID 14757747)
  • 9
  • Data Source:
  • HPRD (in vivo)

SH3BP2

VAV3

Description SH3 domain binding protein 2 vav guanine nucleotide exchange factor 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
  • Asthma and hay fever ( 24388013)
  • Autoimmune thyroid disease ( 32581359)
  • Bipolar disorder ( 31043756)
  • Differentiated thyroid cancer ( 28703219)
  • Eosinophil percentage of white cells ( 32888494)
  • Facial wrinkles (principal components analysis) ( 33959940)
  • Hashimoto thyroiditis versus Graves' disease ( 25429627)
  • Hip circumference adjusted for BMI ( 28552196)
  • Hypothyroidism ( 30367059 27182965 22493691)
  • IgA nephropathy ( 25305756)
  • Medication use (thyroid preparations) ( 31015401)
  • Night sleep phenotypes ( 27126917)
  • Papillary thyroid cancer ( 28703219)
  • Plasma thyroid-stimulating hormone levels ( 24722205)
  • Refractive error ( 32231278)
  • Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Thyroid stimulating hormone levels ( 32769997)
  • Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes 32 interacting genes: ABL1 ARHGAP10 CTTN DBNL ERBB2 ERBB3 ERBB4 FGFR1 FLT3 FYN GRB2 HCLS1 KIT LAT LCK MET MYO1F NSD2 PDLIM7 PLCG1 PLCG2 SH3KBP1 SH3RF1 STAT3 SYK TF TNKS2 VAV1 VAV2 VAV3 YWHAQ ZAP70 25 interacting genes: AR CBLB EGFR ERBB2 ERBB3 ERBB4 ESR1 GAB1 GRB2 IGF1R INSR KIT LCP2 MET PIK3R1 PLCG1 RAC1 RHOA RHOG RINT1 ROS1 SH3BP2 SHC1 ZRANB1 ZYX
Entrez ID 6452 10451
HPRD ID 03657 05706
Ensembl ID ENSG00000087266 ENSG00000134215
Uniprot IDs A0A384N6E5 P78314 Q9UKW4
PDB IDs 2CR4 3TWR 2D86
Enriched GO Terms of Interacting Partners?
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