SFTPC and LSMEM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SFTPC	LSMEM2
Description		surfactant protein C	leucine rich single-pass membrane protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Alveolar Lamellar Body Multivesicular Body Lumen	Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Respiratory Gaseous Exchange By Respiratory System
Pathways		Surfactant metabolism Defective pro-SFTPC causes SMDP2 and RDS Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		36 interacting genes: BSCL2 CD200R1 CD79A CLDN5 CPLX4 CREB3 CXCL9 FAM209A FNDC9 GJA8 GOLM1 GPR152 GPX8 HPN ICAM3 IFNGR2 KLRC1 LMNA LSMEM2 MUC1 NEDD4 PDZK1IP1 PQBP1 PVR SEC22A SEC61G SIGLEC9 SMIM3 SYNE4 TMEM106C TMEM139 TMEM30B TMEM79 TMPRSS2 WWP1 WWP2	20 interacting genes: APP CD72 CLDN7 CLEC12B CTXN3 CXCL9 EMP1 GIMAP5 KLRC1 LSMEM1 PLN SEC22A SFTPC SGTA SMIM3 SPACA1 SPG21 STX7 TMEM143 TMEM218
Entrez ID		6440	132228
HPRD ID		01520	08789
Ensembl ID		ENSG00000168484	ENSG00000179564
Uniprot IDs		A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686	Q8N112
PDB IDs		2YAD
Enriched GO Terms of Interacting Partners?
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