LSMEM2 and CLEC12B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LSMEM2	CLEC12B
Description		leucine rich single-pass membrane protein 2	C-type lectin domain family 12 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	External Side Of Plasma Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Phosphatase Binding Carbohydrate Binding Signaling Receptor Inhibitor Activity
	Biological Process		Natural Killer Cell Inhibitory Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Malaria ( 31844061) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		20 interacting genes: APP CD72 CLDN7 CLEC12B CTXN3 CXCL9 EMP1 GIMAP5 KLRC1 LSMEM1 PLN SEC22A SFTPC SGTA SMIM3 SPACA1 SPG21 STX7 TMEM143 TMEM218	11 interacting genes: IL1RL1 JAGN1 LPAR3 LSMEM2 MALL OPRM1 PLLP PMP22 SCD SEC22A VMA21
Entrez ID		132228	387837
HPRD ID		08789	18266
Ensembl ID		ENSG00000179564	ENSG00000256660
Uniprot IDs		Q8N112	A0A140VK10 Q2HXU8
PDB IDs
Enriched GO Terms of Interacting Partners?
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