SRSF5 and HIPK3

Number of citations of the paper that reports this interaction (PubMedID 16000324)
27

Data Source:
BioGRID (unspecified method)

		SRSF5	HIPK3
Description		serine and arginine rich splicing factor 5	homeodomain interacting protein kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Nuclear Speck	Nucleus Cytoplasm Cytosol Plasma Membrane Nuclear Body PML Body
	Molecular Function	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Serine Kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Cellular Response To Insulin Stimulus Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Liver Regeneration	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Fostamatinib
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Anger ( 24489884) Obese vs. thin ( 30677029) Sleep (1/3-day periodicity) ( 33075057) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		20 interacting genes: CALM1 CCR2 CD101 CLK1 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRPK2 SRSF1 TIAM1 TNK2 ZRSR2	38 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I WT1 ZNF107 ZYX
Entrez ID		6430	10114
HPRD ID		02948	05111
Ensembl ID		ENSG00000100650	ENSG00000110422
Uniprot IDs		A0A024R6D8 Q13243 Q86U32	A8KAE4 Q9H422
PDB IDs
Enriched GO Terms of Interacting Partners?
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