ZBED8 and MBTPS1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		ZBED8	MBTPS1
Description		zinc finger BED-type containing 8	membrane bound transcription factor peptidase, site 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Golgi Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Integral Component Of Membrane
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity
	Biological Process		Proteolysis Lysosome Organization Cholesterol Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Membrane Protein Intracellular Domain Proteolysis Response To Endoplasmic Reticulum Stress ATF6-mediated Unfolded Protein Response Regulation Of Cholesterol Biosynthetic Process Regulation Of Vesicle-mediated Transport
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) ATF6 (ATF6-alpha) activates chaperones Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) CREB3 factors activate genes CREB3 factors activate genes Post-translational protein phosphorylation Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS			Iris color (a* coordinate) ( 30895295) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		12 interacting genes: CEP126 DDIT4L EED EEF1G HAVCR2 HSF4 MBTPS1 MEOX2 METTL21A NAB2 REL SLU7	10 interacting genes: ATF6B BDNF BIRC3 C11orf58 CANX CDK2AP2 SPHK1 TNFRSF14 TNFSF11 ZBED8
Entrez ID		63920	8720
HPRD ID		17430	04522
Ensembl ID		ENSG00000221886	ENSG00000140943
Uniprot IDs		Q8IZ13	Q14703
PDB IDs
Enriched GO Terms of Interacting Partners?
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