UBE2O and MXI1

Number of citations of the paper that reports this interaction (PubMedID 32901121)
2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		UBE2O	MXI1
Description		ubiquitin conjugating enzyme E2 O	MAX interactor 1, dimerization protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Protein Monoubiquitination Negative Regulation Of Endopeptidase Activity Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Protein K63-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mitochondrial DNA levels ( 25240745) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)	Birth weight ( 31043758) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Neutrophil count ( 29403010 32888494) Normalized brain volume ( 19010793) Platelet count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010 32888494)
Interacting Genes		18 interacting genes: APPL1 BAP1 CPNE1 CPNE2 CPNE4 HEXIM1 ITCH MAF MDM2 MXI1 PRKN RNF10 RNF31 SFMBT2 SHBG TRIM27 UBC UBE2D3	29 interacting genes: APP CALCOCO2 CYSRT1 EFEMP2 ENTPD5 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-7 MAX MDFI MYC NBPF19 NOTCH2NLA PEAR1 RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 UBE2O USHBP1 ZNF655
Entrez ID		63893	4601
HPRD ID		10928	02486
Ensembl ID		ENSG00000175931	ENSG00000119950
Uniprot IDs		Q9C0C9	A0A0S2Z3X5 P50539
PDB IDs
Enriched GO Terms of Interacting Partners?
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