MXI1 and PEAR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MXI1	PEAR1
Description		MAX interactor 1, dimerization protein	platelet endothelial aggregation receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex	Phagocytic Cup Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	Protein Binding Signaling Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Phosphatidylinositol 3-kinase Signaling Protein Kinase B Signaling Recognition Of Apoptotic Cell Platelet Aggregation
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Neutrophil count ( 29403010 32888494) Normalized brain volume ( 19010793) Platelet count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010 32888494)	Blood protein levels ( 30072576 29875488) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Mean platelet volume ( 32888494 27863252) Platelet aggregation ( 20526338 29185836) Platelet count ( 29403010 32888494) Platelet distribution width ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		29 interacting genes: APP CALCOCO2 CYSRT1 EFEMP2 ENTPD5 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-7 MAX MDFI MYC NBPF19 NOTCH2NLA PEAR1 RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 UBE2O USHBP1 ZNF655	3 interacting genes: KRTAP4-5 MXI1 NUFIP2
Entrez ID		4601	375033
HPRD ID		02486	18957
Ensembl ID		ENSG00000119950	ENSG00000187800
Uniprot IDs		A0A0S2Z3X5 P50539	Q5VY43
PDB IDs
Enriched GO Terms of Interacting Partners?
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