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CCL19 and ATP6V0B
CCL19
ATP6V0B
Description
C-C motif chemokine ligand 19
ATPase H+ transporting V0 subunit b
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Lysosomal Membrane
Endosome Membrane
Integral Component Of Membrane
Phagocytic Vesicle Membrane
Proton-transporting V-type ATPase, V0 Domain
Molecular Function
Protein Binding
Chemokine Activity
CCR7 Chemokine Receptor Binding
CCR10 Chemokine Receptor Binding
Chemokine Receptor Binding
CCR Chemokine Receptor Binding
Transporter Activity
Protein Binding
Proton Transmembrane Transporter Activity
Biological Process
Establishment Of T Cell Polarity
Immunological Synapse Formation
Dendritic Cell Chemotaxis
Myeloid Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Cellular Calcium Ion Homeostasis
Inflammatory Response
Immune Response
Cell Communication
G Protein-coupled Receptor Signaling Pathway
Response To Virus
Positive Regulation Of Glycoprotein Biosynthetic Process
Neutrophil Chemotaxis
T Cell Costimulation
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Tumor Necrosis Factor Production
Response To Prostaglandin E
Positive Regulation Of T Cell Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Lymphocyte Chemotaxis
Positive Regulation Of Receptor-mediated Endocytosis
Cell Maturation
Positive Regulation Of Chemotaxis
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Protein Kinase B Signaling
Regulation Of Cell Projection Assembly
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Response To Nitric Oxide
Positive Regulation Of Neutrophil Chemotaxis
Mature Conventional Dendritic Cell Differentiation
Cellular Response To Virus
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Cell Motility
Positive Regulation Of Dendritic Cell Dendrite Assembly
Negative Regulation Of Dendritic Cell Apoptotic Process
Regulation Of Macroautophagy
Proton Transmembrane Transport
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
ROS and RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Amino acids regulate mTORC1
Ion channel transport
Drugs
Tiludronic acid
Diseases
GWAS
Metabolite levels (
23823483
)
Rheumatoid arthritis (
30423114
24390342
)
Autism spectrum disorder or schizophrenia (
28540026
)
Interacting Genes
18 interacting genes:
ACKR2
ACKR4
ATP6V0B
B4GALT1
CCL22
CCR10
CCR7
CNTFR
CXCL13
DCTN3
FZD7
GALT
MEOX2
PAX5
PF4V1
PPM1E
RPS4X
TLN1
34 interacting genes:
ADGRG3
ADRB2
APOD
BPI
CCL19
COL4A5
DAPK2
EMP1
FAM210B
FAS
GJA8
GPR42
GPR61
INSIG2
IRAK3
KLRC1
MFF
MIP
MS4A3
MTNR1B
NRM
RPS26P15
SLC10A1
SLC2A5
SNTA1
SPACA1
STOM
TM4SF19
TMEM242
TTC39A
VMA21
YWHAE
YWHAG
ZFYVE9
Entrez ID
6363
533
HPRD ID
03750
04759
Ensembl ID
ENSG00000172724
ENSG00000117410
Uniprot IDs
Q6IBD6
Q99731
E9PNL3
Q99437
PDB IDs
2MP1
6WLW
6WM2
6WM3
6WM4
Enriched GO Terms of Interacting Partners
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