RPS6KA2 and MAP2K1

  • Number of citations of the paper that reports this interaction (PubMedID 8939914)
  • 46
  • Data Source:
  • HPRD (in vitro)

RPS6KA2

MAP2K1

Description ribosomal protein S6 kinase A2 mitogen-activated protein kinase kinase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alzheimer's disease progression score ( 29860282)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Blood pressure (smoking interaction) ( 25189868)
  • Café-au-lait macule number in neurofibromatosis type1 ( 32869517)
  • Dental caries ( 23259602)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Inflammatory bowel disease ( 27569725 23128233)
  • Macrovascular complications in type 2 diabetes ( 33430853)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Smooth-surface caries ( 24556642)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Waist circumference ( 28552196)
Interacting Genes 19 interacting genes: AFDN BAD CREB1 DYNLT1 DYNLT2 FLNC FOS JUN KCNJ6 L1CAM MAGI1 MAP2K1 MAPK1 MAPK3 OTUD4 SHANK1 TBXT THBS2 TP53 67 interacting genes: APC ARAF AURKA BANP BAX BIRC6 BMPR1A BRAF BUB1 CASP9 CDH1 CDK5 CDKN2A CPNE1 CPNE4 CTNNA1 EGFR ELK1 EP300 ERBB2 FBXW7 GRB10 HNRNPD HRAS ITCH KAT7 KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MBP MLH3 MSH6 MYC ODC1 PAK1 PARVA PDGFRL PEBP1 PEBP4 PIK3CA PLEKHF2 PLK3 PPARG PRKCI PRKCZ PTPRJ RAF1 RPS6KA2 RPS6KA4 SMAD2 SRC STK11 TCP11 TGFBR2 TLR2 TRAF3 TRAF6 TRIB1 UBE2I WNK1
Entrez ID 6196 5604
HPRD ID 03403 01469
Ensembl ID ENSG00000071242 ENSG00000169032
Uniprot IDs B7Z3B5 Q15349 X5D337 A4QPA9 B4DFY5 H3BRW9 Q02750
PDB IDs 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3W8Q 3WIG 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 4LMN 4MNE 4U7Z 4U80 4U81 5BX0 5EYM 5HZE 5YT3 6NYB 6PP9 6Q0J 6Q0T 6U2G 6V2V 6V2W 6V2X 6V2Y 6V2Z 6V30 6V31 6V32 6X2P 6X2S 6X2X 7B3M 7B7R 7B94 7B9L
Enriched GO Terms of Interacting Partners?
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