MAP2K1 and KSR1

  • Number of citations of the paper that reports this interaction (PubMedID 11940661)
  • 108
  • Data Source:
  • HPRD (in vivo)

MAP2K1

KSR1

Description mitogen-activated protein kinase kinase 1 kinase suppressor of ras 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Monocyte count ( 32888494 27863252)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 67 interacting genes: APC ARAF AURKA BANP BAX BIRC6 BMPR1A BRAF BUB1 CASP9 CDH1 CDK5 CDKN2A CPNE1 CPNE4 CTNNA1 EGFR ELK1 EP300 ERBB2 FBXW7 GRB10 HNRNPD HRAS ITCH KAT7 KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MBP MLH3 MSH6 MYC ODC1 PAK1 PARVA PDGFRL PEBP1 PEBP4 PIK3CA PLEKHF2 PLK3 PPARG PRKCI PRKCZ PTPRJ RAF1 RPS6KA2 RPS6KA4 SMAD2 SRC STK11 TCP11 TGFBR2 TLR2 TRAF3 TRAF6 TRIB1 UBE2I WNK1 10 interacting genes: BRAP EPHB2 ITCH MAP2K1 MAPK1 MARK3 NME1 PJA2 RAF1 YWHAZ
Entrez ID 5604 8844
HPRD ID 01469 18980
Ensembl ID ENSG00000169032 ENSG00000141068
Uniprot IDs A4QPA9 B4DFY5 H3BRW9 Q02750 Q8IVT5
PDB IDs 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3W8Q 3WIG 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 4LMN 4MNE 4U7Z 4U80 4U81 5BX0 5EYM 5HZE 5YT3 6NYB 6PP9 6Q0J 6Q0T 6U2G 6V2V 6V2W 6V2X 6V2Y 6V2Z 6V30 6V31 6V32 6X2P 6X2S 6X2X 7B3M 7B7R 7B94 7B9L 5VYK 7JUW 7JUX 7JUY 7JUZ 7JV0 7JV1
Enriched GO Terms of Interacting Partners?
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