RPL30 and OAS1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RPL30	OAS1
Description		ribosomal protein L30	2'-5'-oligoadenylate synthetase 1
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GO Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Polysomal Ribosome Extracellular Exosome	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Cytoplasmic Translation Translation Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Glucose Metabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Interferon-beta Glucose Homeostasis Defense Response To Bacterium Surfactant Homeostasis Negative Regulation Of Viral Genome Replication Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Ribonuclease Activity Interleukin-27-mediated Signaling Pathway Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of IP-10 Production Cellular Response To Virus Antiviral Innate Immune Response Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs			Cysteine-S-acetamide
Diseases
GWAS		Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Glycemic traits ( 23575436) Low HDL-cholesterol levels ( 31006500) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239) Urate levels ( 31578528)
Interacting Genes		16 interacting genes: APP CASP2 DUX4 ERCC6 FAM120B G0S2 IL7R MAP2K7 MAP3K14 NEDD4L NFKB2 OAS1 OGT PRKAR2B PTEN ZFAND2A	11 interacting genes: ACTN1 BBS4 BUD23 COG6 EXOC5 GOLGA2 HOOK2 PRMT6 RPL30 RUFY1 TRIM27
Entrez ID		6156	4938
HPRD ID		01595	08879
Ensembl ID		ENSG00000156482	ENSG00000089127
Uniprot IDs		A0A024R9D3 P62888	P00973
PDB IDs		3VI6 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP	4IG8
Enriched GO Terms of Interacting Partners?
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