OAS1

Description		2'-5'-oligoadenylate synthetase 1
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Membrane
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Glucose Metabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Interferon-beta Glucose Homeostasis Defense Response To Bacterium Surfactant Homeostasis Negative Regulation Of Viral Genome Replication Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Ribonuclease Activity Interleukin-27-mediated Signaling Pathway Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of IP-10 Production Cellular Response To Virus Antiviral Innate Immune Response Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways		Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs		Cysteine-S-acetamide
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Glycemic traits ( 23575436) Low HDL-cholesterol levels ( 31006500) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239) Urate levels ( 31578528)
Interacting Genes		11 interacting genes: ACTN1 BBS4 BUD23 COG6 EXOC5 GOLGA2 HOOK2 PRMT6 RPL30 RUFY1 TRIM27
Entrez ID		4938
HPRD ID		08879
Ensembl ID		ENSG00000089127
Uniprot IDs		P00973
PDB IDs		4IG8
Enriched GO Terms of Interacting Partners?
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