RFX2 and EYA2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

RFX2

EYA2

Description regulatory factor X2 EYA transcriptional coactivator and phosphatase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 32296059)
  • Body fat percentage and triglycerides (pairwise) ( 33619380)
  • Body shape index ( 34021172)
  • Brain volume in infants (intracranial brain volume) ( 28763065)
  • Coffee consumption ( 31046077)
  • Fasting insulin ( 34059833)
  • FEV1 ( 30804560)
  • Glaucoma (primary open-angle) ( 33627673)
  • Heel bone mineral density ( 30598549 28869591)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (FVC) ( 30061609 30804560)
  • Non-del(5q) myelodysplastic syndromes ( 31738830)
  • Peak expiratory flow ( 30804560)
  • Reticulocyte count ( 32888494)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Triglyceride levels ( 32203549 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 2 diabetes ( 30054458 30297969)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 17 interacting genes: C1orf94 EYA2 FOXJ1 FOXN4 HNRNPM ICAM3 MDFI MYO1F NFKBID PIAS2 RFX1 RFX4 RFX6 SAFB SNAPC2 STXBP2 ZNF14 36 interacting genes: AATK BAG3 CATSPER1 CDK18 DMRTB1 DTX2 DUSP21 ENKD1 FAM214B GNAI2 GNAZ HGS IQUB LGALS4 LOX MED25 PATZ1 PAX9 PIN1 POGZ RBPMS RFX2 ROR2 SIX1 SIX4 SNRPC SPG21 SUOX TEKT4 TEKT5 TFG TLE5 TRAF4 TRAPPC6A TSSK3 VPS37C
Entrez ID 5990 2139
HPRD ID 00824 09041
Ensembl ID ENSG00000087903 ENSG00000064655
Uniprot IDs P48378 E7ETN2 O00167
PDB IDs 3GEB 3HB0 3HB1 4EGC 5ZMA
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?