REN and AGT

  • Number of citations of the paper that reports this interaction (PubMedID 12045255)
  • 385
  • Data Source:
  • BioGRID (enzymatic study, x-ray crystallography, enzymatic study)

REN

AGT

Description renin angiotensinogen
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 29875488)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
  • Blood protein levels ( 30072576)
  • Coronary artery disease ( 29212778 33020668)
  • Diastolic blood pressure ( 27841878 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean arterial pressure ( 27618448)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Pancreatic ductal adenocarcinoma ( 30541042)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
  • Systolic blood pressure ( 27841878 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 9 interacting genes: AGT ATP6AP2 CCDC24 CTSB KCTD15 M6PR PCSK1 PCSK5 RENBP 24 interacting genes: ACE2 AGTR1 AGTR2 ATP6AP2 CMA1 CTSG DNPEP ECE1 ENPEP EWSR1 GRB2 GSDMB HSP90AA1 ITSN2 KNG1 LNPEP MAS1 MEP1A MME PRCP PREP PRG2 REN TP53
Entrez ID 5972 183
HPRD ID 01564 00106
Ensembl ID ENSG00000143839 ENSG00000135744
Uniprot IDs P00797 B0ZBE2 B2R5S1 P01019
PDB IDs 1BBS 1BIL 1BIM 1HRN 1RNE 2BKS 2BKT 2FS4 2G1N 2G1O 2G1R 2G1S 2G1Y 2G20 2G21 2G22 2G24 2G26 2G27 2I4Q 2IKO 2IKU 2IL2 2REN 2V0Z 2V10 2V11 2V12 2V13 2V16 2X0B 3D91 3G6Z 3G70 3G72 3GW5 3K1W 3KM4 3O9L 3OAD 3OAG 3OOT 3OQF 3OQK 3OWN 3Q3T 3Q4B 3Q5H 3SFC 3VCM 3VSW 3VSX 3VUC 3VYD 3VYE 3VYF 4AMT 4GJ5 4GJ6 4GJ7 4GJ8 4GJ9 4GJA 4GJB 4GJC 4GJD 4PYV 4Q1N 4RYC 4RYG 4RZ1 4S1G 4XX3 4XX4 5KOQ 5KOS 5KOT 5SXN 5SY2 5SY3 5SZ9 5T4S 5TMG 5TMK 5V8V 5VPM 5VRP 6I3F 1N9U 1N9V 2JP8 2WXW 2X0B 3CK0 3WOO 3WOR 4AA1 4APH 4FYS 5E2Q 5M3X 5M3Y 5XJM 6I3F 6I3I 6JOD 6OS0 7C6A
Enriched GO Terms of Interacting Partners?
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