AGT and ATP6AP2

  • Number of citations of the paper that reports this interaction (PubMedID 20927107)
  • 73
  • Data Source:
  • BioGRID (enzymatic study)

AGT

ATP6AP2

Description angiotensinogen ATPase H+ transporting accessory protein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Coronary artery disease ( 29212778 33020668)
  • Diastolic blood pressure ( 27841878 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean arterial pressure ( 27618448)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Pancreatic ductal adenocarcinoma ( 30541042)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
  • Systolic blood pressure ( 27841878 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 24 interacting genes: ACE2 AGTR1 AGTR2 ATP6AP2 CMA1 CTSG DNPEP ECE1 ENPEP EWSR1 GRB2 GSDMB HSP90AA1 ITSN2 KNG1 LNPEP MAS1 MEP1A MME PRCP PREP PRG2 REN TP53 21 interacting genes: ADRA1A AGT BBS1 CD72 CREB3 GLP1R HTR2C NKG7 NSG1 PMP22 PTTG1IP REN RPGR SEC22A TIMMDC1 TMEM203 TMEM97 UPK2 VAMP5 VKORC1 ZBTB16
Entrez ID 183 10159
HPRD ID 00106 06454
Ensembl ID ENSG00000135744 ENSG00000182220
Uniprot IDs B0ZBE2 B2R5S1 P01019 O75787
PDB IDs 1N9U 1N9V 2JP8 2WXW 2X0B 3CK0 3WOO 3WOR 4AA1 4APH 4FYS 5E2Q 5M3X 5M3Y 5XJM 6I3F 6I3I 6JOD 6OS0 7C6A 3LBS 3LC8 6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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