RAP1B and RAPGEF1

  • Number of citations of the paper that reports this interaction (PubMedID 8524240)
  • 81
  • Data Source:
  • HPRD (in vitro, in vivo)

RAP1B

RAPGEF1

Description RAP1B, member of RAS oncogene family Rap guanine nucleotide exchange factor 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Femoral neck bone mineral density ( 32239398)
  • Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • White blood cell count ( 20139978)
  • Cerebrospinal fluid α-synuclein levels ( 29959729)
  • Cutaneous malignant melanoma ( 32341527)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Kidney volume ( 34128465)
  • Nevus count or cutaneous melanoma ( 32341527)
  • Optic disc size ( 31809533)
Interacting Genes 30 interacting genes: A2M ALAS1 APLP1 APP CCT7 CHGB CSAD DDAH2 FAF1 HRAS KMT2B LRIF1 MTUS2 PDHB PKM PRKACA RAB7B RALGDS RAPGEF1 RASSF5 RGL2 RGS2 RPTOR SDF4 SMURF2 TLE1 TP53 UNC119 ZDHHC17 ZNF135 20 interacting genes: ABL1 ATXN1 BCAR1 CRK CRKL EGFR GRB2 HCK HRAS MBIP NEDD9 PDGFRA RAP1A RAP1B RAP2B RHOQ RPS15 RRAS2 SHC1 SLC20A1
Entrez ID 5908 2889
HPRD ID 01546 02627
Ensembl ID ENSG00000127314 ENSG00000107263
Uniprot IDs A0A024RB87 B7ZAY2 P61224 Q13905
PDB IDs 3BRW 3CF6 4DXA 4HDO 4HDQ 4M8N 4MGI 4MGK 4MGY 4MGZ 4MH0 5KHO 6AXF 6BA6 6KYK 6OQ3 6OQ4 6UZK 5L23
Enriched GO Terms of Interacting Partners?
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