RAPGEF1 and CRKL

  • Number of citations of the paper that reports this interaction (PubMedID 26496610)
  • 430
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

RAPGEF1

CRKL

Description Rap guanine nucleotide exchange factor 1 CRK like proto-oncogene, adaptor protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebrospinal fluid α-synuclein levels ( 29959729)
  • Cutaneous malignant melanoma ( 32341527)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Kidney volume ( 34128465)
  • Nevus count or cutaneous melanoma ( 32341527)
  • Optic disc size ( 31809533)
Interacting Genes 20 interacting genes: ABL1 ATXN1 BCAR1 CRK CRKL EGFR GRB2 HCK HRAS MBIP NEDD9 PDGFRA RAP1A RAP1B RAP2B RHOQ RPS15 RRAS2 SHC1 SLC20A1 79 interacting genes: ABL1 AOX1 AREL1 ARHGAP32 BCAR1 BCR BIK BLK BLNK CBL CBLB CD34 CHEK2 CRK DAB1 DOCK2 DOK1 DOK2 EPHB6 EPOR ERBB2 ERBB3 ETV6 EVL FCGR1A GAB1 GAB2 GAREM1 GRB2 GRN IFNAR1 IGF1R INPP5D INSR IRS4 ITGB1 KHDRBS1 KIDINS220 KIT LAMA5 LTBP4 LYN MAP4K1 MAP4K5 MEGF6 MSL1 NEDD9 NOTCH2 PDGFRA PHC2 PIK3R1 PIK3R2 PLEKHA1 PLSCR1 POLR1D PPFIBP2 PSMC6 PTPDC1 PTPN11 PXN RAPGEF1 RPL31 SASH1 SHANK3 SHC1 SOS1 SOS2 STAT5A STAT5B SYK TGFB1I1 TMEM168 TYK2 USP53 WAC WAS WIPF1 YES1 YY1
Entrez ID 2889 1399
HPRD ID 02627 03596
Ensembl ID ENSG00000107263 ENSG00000099942
Uniprot IDs Q13905 P46109
PDB IDs 5L23 2BZX 2BZY 2DBK 2EO3 2LQN 2LQW
Enriched GO Terms of Interacting Partners?
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